Vitamin B3
Commonly known as Niacin, it has anti-inflammatory and skin-brightening properties.
What to Avoid Mixing With
Niacinamide and vitamin C are generally safe to layer — older concerns about flushing are largely debunked at normal usage concentrations. If your skin is very sensitive, wait a few minutes between application.
AHAs lower skin pH while niacinamide works best at neutral pH. Together they may reduce niacinamide's effectiveness. Consider using on alternate routines.
Great combo! Niacinamide soothes inflammation and strengthens the barrier, making retinoid easier to tolerate.
Excellent pair! Hyaluronic acid hydrates while niacinamide strengthens the skin barrier. Use together for plump, healthy skin.
Niacinamide + salicylic acid is a power duo for oily and acne-prone skin. Niacinamide calms any irritation from the BHA.
Both strengthen the skin barrier through different mechanisms. Together they're the ultimate barrier repair combo.
Niacinamide and zinc together are great for oily and acne-prone skin. They reduce sebum and calm inflammation.
Azelaic acid and niacinamide work synergistically for brightening. Both target hyperpigmentation through different pathways.
Centella soothes while niacinamide strengthens. Together they calm redness and rebuild the skin barrier.
Snail mucin and niacinamide are excellent together. Snail mucin hydrates and repairs while niacinamide brightens and strengthens.
Growth Factors
PDRN/EGF pairs well with niacinamide. Both support skin repair through different pathways without any conflicts.
Fermented Ingredients
Fermented ingredients like galactomyces enhance absorption of niacinamide. A staple K-beauty combination.
Tranexamic acid and niacinamide are a brightening power duo. Both fade dark spots through different mechanisms.
Zinc + niacinamide is a classic for oily/acne-prone skin. They regulate sebum and reduce inflammation together.
Peptides
Peptides and niacinamide both support the skin barrier and collagen. Safe and beneficial to combine.
Arbutin and niacinamide are a gentle brightening duo. Both target melanin through different pathways and are safe to layer together.
Kojic Acid
Kojic acid and niacinamide are a gentle brightening duo. Kojic acid inhibits tyrosinase while niacinamide blocks melanosome transfer — complementary pathways with no conflict.