Ceramide Np

Goodactive

A specific type of ceramide that is a key component of the skin barrier, helping to lock in moisture.

What is Ceramide Np?

CAS Number

100403-19-8

Formula

C34H67NO4

Molecular Weight

565.90 g/mol

Also known as: Ceramide 3, N-Stearoylphytosphingosine, Ceramide III

What does Ceramide Np do for skin?

Major component of the stratum corneum lipid matrix (forms lamellar bilayers with cholesterol and free fatty acids in a 1:1:1 molar ratio). Replenishes depleted ceramides in damaged or aged skin. Restores barrier function by reducing transepidermal water loss (TEWL). Signals keratinocyte differentiation and apoptosis regulation via sphingolipid signaling pathways.

Typical concentration: 0.01-0.5% (typically used in combination with other ceramides)

Is Ceramide Np safe?

No known adverse effects. Identical to naturally occurring skin ceramides. CIR Expert Panel: safe as used in cosmetics.

What does the research say about Ceramide Np?

Regulatory Info

Status: Approved
Restrictions: Ceramide NP,1,3,4-Octadecanetriol, 2-Octadecanamide,Stearoyl-C18-Phytosphingosine,Stearoyl-4-Hydroxysphinganine

Can I mix Ceramide Np with other ingredients?

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General guidance

Ceramides are excellent after exfoliation. They repair and strengthen the skin barrier that acids temporarily weaken.

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Niacinamide

Both strengthen the skin barrier through different mechanisms. Together they're the ultimate barrier repair combo.

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Retinoids

Ceramides help counteract retinoid dryness. Apply ceramide moisturizer after retinoid for better tolerance.

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AHAs (Glycolic, Lactic, etc.)

Glycolic acid + ceramides is a smart pairing. The acid exfoliates while ceramides immediately repair the barrier.

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Centella Asiatica (Cica)

Centella and ceramides together are the ultimate barrier repair duo. Both soothe and strengthen damaged or sensitized skin.

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Growth Factors

Ceramides create a protective barrier that helps growth factors stay active on the skin longer.

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Hyaluronic Acid

HA draws water in, ceramides lock it in. Apply HA on damp skin first, then ceramide moisturizer to seal.

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Peptides

Peptides and ceramides are both gentle and reparative. A perfect combo for anti-aging without irritation.

Read all ingredient interaction guides for layering order and science-backed advice.

All Ingredients

Frequently Asked Questions

What does Ceramide Np do in skincare?+

A specific type of ceramide that is a key component of the skin barrier, helping to lock in moisture. Major component of the stratum corneum lipid matrix (forms lamellar bilayers with cholesterol and free fatty acids in a 1:1:1 molar ratio). Replenishes depleted ceramides in damaged or aged skin. Restores barrier function by reducing transepidermal water loss (TEWL). Signals keratinocyte differentiation and apoptosis regulation via sphingolipid signaling pathways.

Is Ceramide Np safe for sensitive skin?+

No known adverse effects. Identical to naturally occurring skin ceramides. CIR Expert Panel: safe as used in cosmetics.

What percentage of Ceramide Np should I look for?+

Look for products with 0.01-0.5% (typically used in combination with other ceramides) for clinical efficacy.

Can I use Ceramide Np with General guidance?+

Ceramide Np can be used with General guidance. Ceramides are excellent after exfoliation. They repair and strengthen the skin barrier that acids temporarily weaken.

Can I use Ceramide Np with Niacinamide?+

Ceramide Np can be used with Niacinamide. Both strengthen the skin barrier through different mechanisms. Together they're the ultimate barrier repair combo.

Can I use Ceramide Np with Retinoids?+

Ceramide Np can be used with Retinoids. Ceramides help counteract retinoid dryness. Apply ceramide moisturizer after retinoid for better tolerance.

Can I use Ceramide Np with AHAs (Glycolic, Lactic, etc.)?+

Ceramide Np can be used with AHAs (Glycolic, Lactic, etc.). Glycolic acid + ceramides is a smart pairing. The acid exfoliates while ceramides immediately repair the barrier.

Further Reading

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