Asiaticoside
A triterpenoid from Centella Asiatica that aids in skin soothing and healing.
What is Asiaticoside?
CAS Number
16830-15-2
Formula
C48H78O19
Molecular Weight
959.1 g/mol
Also known as: Asiaticoside, Madecassol, Asiaticosid, Centelase, Emdecassol
What does Asiaticoside do for skin?
Asiaticoside, a triterpene saponin from Centella asiatica, primarily promotes dermal repair and anti-inflammatory responses. It stimulates fibroblast proliferation and enhances the synthesis of type I and III collagen, fibronectin, and glycosaminoglycans, crucial for skin matrix regeneration and tensile strength. Its anti-inflammatory action involves modulating pro-inflammatory cytokines, inhibiting NF-κB activation, and reducing oxidative stress, which collectively aid in wound healing and soothing irritated skin.
Typical concentration: 0.05-1.0% (most formulas use 0.1-0.5%)
Is Asiaticoside safe?
Asiaticoside is generally considered safe for topical application. The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Centella Asiatica Extract and its constituents, including asiaticoside, are safe in cosmetic formulations at current practices of use and concentration.
What does the research say about Asiaticoside?
Asiaticoside enhances type I and III collagen synthesis in cultured human skin fibroblasts.
Lu L, et al., Chin Med J (Engl), 2004
Liu M, et al., Molecules, 2020
Lin SC, et al., J Cosmet Dermatol, 2020
Regulatory Info
Can I mix Asiaticoside with other ingredients?
Centella and ceramides together are the ultimate barrier repair duo. Both soothe and strengthen damaged or sensitized skin.
Centella soothes while niacinamide strengthens. Together they calm redness and rebuild the skin barrier.
Centella + hyaluronic acid provides deep hydration with calming benefits. Great for sensitive or irritated skin.
Both are K-beauty staples for repair. Snail mucin hydrates while centella calms. Together they accelerate healing.
Centella asiatica is excellent alongside retinoids. It soothes the irritation and redness that retinoids can cause, making your retinoid routine more tolerable.
Growth Factors
Growth factors paired with centella accelerate skin repair and wound healing. Both support tissue regeneration.
Read all ingredient interaction guides for layering order and science-backed advice.