Phenoxyethanol
페녹시에탄올
Preservative used to prevent microbial growth in cosmetic products.
What is Phenoxyethanol?
CAS Number
122-99-6
Formula
C8H10O2
Molecular Weight
138.16 g/mol
Also known as: Phenoxyethanol, Ethylene glycol monophenyl ether, Phenyl cellosolve, Phenoxethol, Phenoxytol
What does Phenoxyethanol do for skin?
Phenoxyethanol functions as a broad-spectrum antimicrobial preservative in cosmetic formulations. It primarily acts by disrupting the cell membranes of bacteria, yeasts, and molds, leading to the leakage of essential intracellular components and inhibition of enzyme systems vital for microbial growth and reproduction, thereby preventing product spoilage and contamination.
Typical concentration: 0.5-1.0% (most formulas use 0.5-1.0%, with 1.0% being the maximum allowed concentration in regions like the EU and Japan).
Is Phenoxyethanol safe?
The Cosmetic Ingredient Review (CIR) Expert Panel has assessed phenoxyethanol as safe for use in cosmetics at concentrations up to 1%. It is generally well-tolerated, but rare cases of contact dermatitis and allergic sensitization have been reported in susceptible individuals, particularly on compromised skin.
What does the research say about Phenoxyethanol?
Final report on the safety assessment of phenoxyethanol.
Andersen FA. Int J Toxicol. 2003;22 Suppl 2:1-12.
Contact allergy to phenoxyethanol: a clinical series.
Maibach AT, Andersen KE, Johansen JD, Lepoittevin JP. Contact Dermatitis. 2005 Dec;53(6):314-8.
Sensitization to phenoxyethanol: a multicenter study.
G. R. E. N. G. Groupe de Recherche et d'Etude en Dermato-Allergologie. Contact Dermatitis. 2011 Dec;65(6):347-51.