Lactobionic Acid

A polyhydroxy acid (PHA) that gently exfoliates, hydrates, and has antioxidant properties. Lactobionic acid, a polyhydroxy acid (PHA), acts as a humectant by attracting and binding water molecules to the skin, enhancing hydration. It provides gentle exfoliation by weakening the ionic bonds between corneocytes in the stratum corneum, promoting natural desquamation with reduced irritation due to its larger molecular size. Furthermore, it functions as an antioxidant, chelating metal ions and scavenging free radicals, thereby protecting skin cells from oxidative stress and contributing to skin barrier maintenance.

Lactobionic acid is generally considered safe and well-tolerated, even for sensitive skin types, owing to its larger molecular size which leads to slower and less irritating penetration compared to alpha-hydroxy acids. The Cosmetic Ingredient Review (CIR) Expert Panel has assessed polyhydroxy acids, including lactobionic acid, as safe for use in cosmetic products. It has a lower potential for irritation and sensitization.

Look for products with Typically used in cosmetic formulations at concentrations ranging from 2% to 15%, with many products utilizing it at 4-10%. for clinical efficacy.

Use Lactobionic Acid with Retinoids carefully. While PHAs are gentler than AHAs, combining with retinoids still increases exfoliation. Monitor for irritation.

Use Lactobionic Acid with AHAs (Glycolic, Lactic, etc.) carefully. Using AHA and PHA together increases total exfoliation. PHAs are gentle but adding them to AHAs may be too much for sensitive skin.