Glycerin
글리세린
A humectant that draws moisture into the skin.
What is Glycerin?
CAS Number
56-81-5
Formula
C3H8O3
Molecular Weight
92.09 g/mol
Also known as: glycerol, glycerin, Glycerine, Glycyl alcohol, Trihydroxypropane
What does Glycerin do for skin?
Glycerin acts as a potent humectant, attracting and binding water from the atmosphere and deeper epidermal layers into the stratum corneum, significantly increasing skin hydration. It also plays a crucial role in maintaining skin barrier function by facilitating water transport through aquaglyceroporins (primarily AQP3) in keratinocytes, which contributes to proper cell maturation and normal desquamation.
Typical concentration: Typically used at 1-10% in most cosmetic formulations, with common usage around 3-5%. It can be found at concentrations up to 40% or higher in specialized products for intense hydration or as a cosolvent.
Is Glycerin safe?
Glycerin is widely recognized as safe (GRAS) by the FDA for topical use and exhibits very low potential for skin irritation or sensitization. The CIR Expert Panel concluded glycerin is safe in cosmetic formulations at concentrations up to 79.9%.
What does the research say about Glycerin?
Glycerin: a moisturizer with a difference
Fluhr JW, Darlenski R, Lademann J. Skin Pharmacol Physiol. 2008;21(3):176-84.
Glycerol and the skin: holistic approach to its role in maintaining barrier function
Atrux-Tallau N, et al. Exp Dermatol. 2010 Sep;19(9):777-85.
Loden M, et al. Skin Res Technol. 2012 Aug;18(3):364-8.