Ethylhexylglycerin
Skin conditioning agent and preservative booster.
What is Ethylhexylglycerin?
CAS Number
70445-33-9
Formula
C11H24O3
Molecular Weight
204.31 g/mol
Also known as: Ethylhexylglycerin, Octoxyglycerin, LADY GOONG, RefChem:57651, Ethylhexylglycerin 0.5%
What does Ethylhexylglycerin do for skin?
Ethylhexylglycerin is a multifunctional ingredient that acts primarily as a preservative enhancer and mild humectant/emollient. It works by reducing the interfacial tension at the cell membranes of microorganisms, disrupting their cell walls and enhancing the penetration of other antimicrobial agents, thereby inhibiting bacterial growth. Additionally, it helps to improve the feel of cosmetic formulations and provides mild emollient properties, contributing to skin conditioning.
Typical concentration: 0.3-1.0% (most formulas use 0.5-0.8%)
Is Ethylhexylglycerin safe?
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that ethylhexylglycerin is safe as a cosmetic ingredient in current practices of use and concentration. It generally has a low potential for skin irritation or sensitization, though hypersensitivity reactions have been reported in rare, susceptible individuals.
What does the research say about Ethylhexylglycerin?
In vitro antibacterial activity of ethylhexylglycerin against skin-related bacteria.
Miyamoto K, Kajiya H, Takechi M. Int J Cosmet Sci. 2023 Feb;45(1):128-132.
Repeated insult patch test on ethylhexylglycerin.
Miyazawa Y, Nakanishi Y, Masuda Y, Masuda K, Taniguchi K. J Dermatol. 2012 Sep;39(9):788-9.
Liceaga CI, Blüthgen N, Thomsen J. J Appl Microbiol. 2021 Dec;131(6):3004-3015.