Bakuchiol

A plant-derived ingredient considered a natural alternative to retinol, offering anti-aging and skin-renewing benefits. Meroterpene from Psoralea corylifolia seeds. Functionally similar to retinol without structural similarity. Upregulates type I and type IV collagen gene expression via retinoid-independent pathway. Antioxidant activity (scavenges DPPH and superoxide radicals). Anti-inflammatory via inhibition of NF-kB and COX-2. Does not cause retinoid-type irritation or photosensitivity.

Well tolerated with no photosensitivity. Safe in pregnancy (unlike retinoids). No retinization period. CIR Expert Panel review pending. Suitable for sensitive skin.

Look for products with 0.5-2% (clinical evidence at 0.5%) for clinical efficacy.

Bakuchiol can be used with Retinoids. Bakuchiol is a gentle retinol alternative. No need to use both unless you want to boost results. Bakuchiol is safer during pregnancy.

Bakuchiol can be used with Vitamin C. Unlike retinol, bakuchiol is stable at low pH and safe to combine with vitamin C. A gentler anti-aging + brightening combo.

Bakuchiol can be used with AHAs (Glycolic, Lactic, etc.). Unlike retinol, bakuchiol is stable at acidic pH and does not conflict with AHAs. No need to separate them — you can safely use both in the same routine.

Bakuchiol can be used with BHAs (Salicylic Acid). Unlike retinol, bakuchiol is pH-stable and safe to combine with BHA (salicylic acid). No need to separate them the way you would with retinol.