Zinc Pca

A mineral salt that helps regulate sebum production and has anti-inflammatory properties. Zinc PCA combines the sebostatic, antimicrobial, and anti-inflammatory properties of zinc with the humectant and skin-penetrating benefits of pyrrolidone carboxylic acid (PCA). Zinc inhibits 5-alpha reductase activity to reduce sebum production, exerts bacteriostatic effects against *Cutibacterium acnes*, and modulates inflammatory cytokine release. PCA, a natural moisturizing factor component, enhances the delivery of zinc into the skin while contributing to hydration and barrier function.

Generally considered safe for cosmetic use. The CIR Expert Panel has deemed zinc salts and PCA safe, and Zinc PCA shows low potential for irritation or sensitization in human repeated insult patch tests.

Look for products with 0.1-2.0% (most formulas use 0.25-1.0%) for clinical efficacy.

Use Zinc Pca with Vitamin C carefully. Zinc can interfere with vitamin C absorption when layered directly. Apply vitamin C first and let it absorb before zinc-based products.

Zinc Pca can be used with Niacinamide. Zinc + niacinamide is a classic for oily/acne-prone skin. They regulate sebum and reduce inflammation together.

Zinc Pca can be used with Niacinamide. Niacinamide and zinc together are great for oily and acne-prone skin. They reduce sebum and calm inflammation.