Tocopherol

토코페롤

Goodantioxidant

A form of Vitamin E that acts as an antioxidant to protect skin from free radical damage.

What is Tocopherol?

CAS Number

1406-66-2

Formula

C28H48O2

Molecular Weight

416.7 g/mol

Also known as: Tocopherols, Methyltocols, R0ZB2556P8, Lasar, UnoVit

What does Tocopherol do for skin?

Tocopherol, a lipophilic antioxidant, primarily functions by scavenging free radicals, such as reactive oxygen species (ROS), generated by UV radiation, pollution, and intrinsic metabolic processes. It donates a hydrogen atom to these highly reactive species, converting them into more stable forms and effectively terminating chain reactions of lipid peroxidation within cell membranes. This action protects cellular components, including lipids, proteins, and DNA, from oxidative damage, thereby supporting skin barrier integrity, reducing inflammation, and mitigating signs of photoaging.

Typical concentration: 0.1-5% (most formulas use 0.5-2% for skin benefits; lower concentrations like 0.05-0.5% are often used as an antioxidant to protect the formula itself).

Is Tocopherol safe?

Tocopherol is generally recognized as safe for use in cosmetics. The CIR Expert Panel has assessed it and found it safe at typical use concentrations. It has a low potential for irritation or sensitization, even at higher concentrations.

What does the research say about Tocopherol?

Regulatory Info

Status: Restricted

Can I mix Tocopherol with other ingredients?

Info

Retinoids

Vitamin E protects retinol from oxidation and helps buffer irritation. Many retinol formulas include vitamin E for exactly this reason — a smart combination for your PM routine.

Info

Vitamin C

Vitamin C and Vitamin E are a synergistic antioxidant duo. Vitamin E stabilizes vitamin C, extending its potency and boosting UV protection together.

Read all ingredient interaction guides for layering order and science-backed advice.

Frequently Asked Questions

What does Tocopherol do in skincare?+

A form of Vitamin E that acts as an antioxidant to protect skin from free radical damage. Tocopherol, a lipophilic antioxidant, primarily functions by scavenging free radicals, such as reactive oxygen species (ROS), generated by UV radiation, pollution, and intrinsic metabolic processes. It donates a hydrogen atom to these highly reactive species, converting them into more stable forms and effectively terminating chain reactions of lipid peroxidation within cell membranes. This action protects cellular components, including lipids, proteins, and DNA, from oxidative damage, thereby supporting skin barrier integrity, reducing inflammation, and mitigating signs of photoaging.

Is Tocopherol safe for sensitive skin?+

Tocopherol is generally recognized as safe for use in cosmetics. The CIR Expert Panel has assessed it and found it safe at typical use concentrations. It has a low potential for irritation or sensitization, even at higher concentrations.

What percentage of Tocopherol should I look for?+

Look for products with 0.1-5% (most formulas use 0.5-2% for skin benefits; lower concentrations like 0.05-0.5% are often used as an antioxidant to protect the formula itself). for clinical efficacy.

Can I use Tocopherol with Retinoids?+

Tocopherol can be used with Retinoids. Vitamin E protects retinol from oxidation and helps buffer irritation. Many retinol formulas include vitamin E for exactly this reason — a smart combination for your PM routine.

Can I use Tocopherol with Vitamin C?+

Tocopherol can be used with Vitamin C. Vitamin C and Vitamin E are a synergistic antioxidant duo. Vitamin E stabilizes vitamin C, extending its potency and boosting UV protection together.

Further Reading