Tocopherol
토코페롤
A form of Vitamin E that acts as an antioxidant to protect skin from free radical damage.
What is Tocopherol?
CAS Number
1406-66-2
Formula
C28H48O2
Molecular Weight
416.7 g/mol
Also known as: Tocopherols, Methyltocols, R0ZB2556P8, Lasar, UnoVit
What does Tocopherol do for skin?
Tocopherol, a lipophilic antioxidant, primarily functions by scavenging free radicals, such as reactive oxygen species (ROS), generated by UV radiation, pollution, and intrinsic metabolic processes. It donates a hydrogen atom to these highly reactive species, converting them into more stable forms and effectively terminating chain reactions of lipid peroxidation within cell membranes. This action protects cellular components, including lipids, proteins, and DNA, from oxidative damage, thereby supporting skin barrier integrity, reducing inflammation, and mitigating signs of photoaging.
Typical concentration: 0.1-5% (most formulas use 0.5-2% for skin benefits; lower concentrations like 0.05-0.5% are often used as an antioxidant to protect the formula itself).
Is Tocopherol safe?
Tocopherol is generally recognized as safe for use in cosmetics. The CIR Expert Panel has assessed it and found it safe at typical use concentrations. It has a low potential for irritation or sensitization, even at higher concentrations.
What does the research say about Tocopherol?
Topical alpha-tocopherol in the prevention and treatment of ultraviolet-induced skin damage.
Burke KE. J Am Acad Dermatol. 1999 Nov;41(5 Pt 1):724-34.
Photoprotective and anti-aging properties of topical vitamin C and E.
Farris PK. Dermatol Surg. 2007 Jul;33(7):808-18.
Keen MA, Hassan I. Antioxidants (Basel). 2024 Jan 12;13(1):103.
Regulatory Info
Can I mix Tocopherol with other ingredients?
Vitamin E protects retinol from oxidation and helps buffer irritation. Many retinol formulas include vitamin E for exactly this reason — a smart combination for your PM routine.
Vitamin C and Vitamin E are a synergistic antioxidant duo. Vitamin E stabilizes vitamin C, extending its potency and boosting UV protection together.
Read all ingredient interaction guides for layering order and science-backed advice.