Sodium Lauryl Sulfate
A strong surfactant that creates a rich lather but can be stripping and irritating for some.
What is Sodium Lauryl Sulfate?
CAS Number
151-21-3
Formula
C12H25NaO4S
Molecular Weight
288.38 g/mol
Also known as: Sodium dodecyl sulfate, SODIUM LAURYL SULFATE, Sodium dodecylsulfate, Sodium lauryl sulphate, Sodium dodecyl sulphate
What does Sodium Lauryl Sulfate do for skin?
Sodium Lauryl Sulfate (SLS) is an anionic surfactant that functions by significantly reducing surface tension. On the skin, it interacts with the lipid matrix and proteins of the stratum corneum. It solubilizes intercellular lipids and denatures keratin, leading to a disruption of the skin barrier function. This disruption increases transepidermal water loss (TEWL) and enhances the penetration of other substances, contributing to its cleansing action and potential for irritation.
Typical concentration: 1-50% (often 1-10% in leave-on or sensitive skin rinse-off products; up to 30% or more in strong foaming cleansers like shampoos).
Is Sodium Lauryl Sulfate safe?
The CIR Expert Panel has deemed Sodium Lauryl Sulfate safe in cosmetic formulations when used in rinse-off products and in leave-on products at concentrations up to 1%. It is a known skin irritant, particularly at higher concentrations or with prolonged exposure, and can cause dryness, redness, and itching, especially in individuals with sensitive skin or a compromised skin barrier, but is not considered a sensitizer.
What does the research say about Sodium Lauryl Sulfate?
Amended Safety Assessment of Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate
Fiume MZ, Bergfeld WF, Belsito DV, et al. International Journal of Toxicology. 2010;29(4_suppl):151S-16 amended report.
Mølhave E, Skou H, Sørensen SM, et al. Int J Cosmet Sci. 2020 Feb;42(1):10-22.
Molecular and biophysical characterization of the skin irritation potential of anionic surfactants
Löffler H, Løland K, Berardesca E, et al. Contact Dermatitis. 2009 Mar;60(3):141-50.