Panthenol

판테놀

Goodvitamin

A humectant and emollient that converts to Vitamin B5 in the skin, known for its moisturizing and soothing properties.

What is Panthenol?

CAS Number

81-13-0

Formula

C9H19NO4

Molecular Weight

205.25 g/mol

Also known as: Dexpanthenol, D-Panthenol, Provitamin B5

What does Panthenol do for skin?

Provitamin converted to pantothenic acid (vitamin B5) in the skin. Pantothenic acid is a component of coenzyme A, essential for lipid synthesis and energy metabolism in cells. Stimulates fibroblast proliferation and accelerates re-epithelialization in wound healing. Acts as a humectant, binding water in the stratum corneum. Anti-inflammatory via reduction of IL-6, IL-8, and TNF-alpha.

Typical concentration: 1-5% (most formulations use 2-5%)

Is Panthenol safe?

Extremely well tolerated. CIR Expert Panel: safe as used in cosmetics. No sensitization potential. Suitable for sensitive and baby skin.

What does the research say about Panthenol?

  • Dexpanthenol in skin care

    Proksch & Nissen, American Journal of Clinical Dermatology, 2002

  • Wound healing effects of panthenol

    Heise et al., Skin Pharmacology and Applied Skin Physiology, 1999

Regulatory Info

Status: Restricted
All Ingredients

Frequently Asked Questions

What does Panthenol do in skincare?+

A humectant and emollient that converts to Vitamin B5 in the skin, known for its moisturizing and soothing properties. Provitamin converted to pantothenic acid (vitamin B5) in the skin. Pantothenic acid is a component of coenzyme A, essential for lipid synthesis and energy metabolism in cells. Stimulates fibroblast proliferation and accelerates re-epithelialization in wound healing. Acts as a humectant, binding water in the stratum corneum. Anti-inflammatory via reduction of IL-6, IL-8, and TNF-alpha.

Is Panthenol safe for sensitive skin?+

Extremely well tolerated. CIR Expert Panel: safe as used in cosmetics. No sensitization potential. Suitable for sensitive and baby skin.

What percentage of Panthenol should I look for?+

Look for products with 1-5% (most formulations use 2-5%) for clinical efficacy.

Further Reading