Methylparaben
메틸파라벤
Preservative that prevents microbial growth.
What is Methylparaben?
CAS Number
99-76-3
Formula
C8H8O3
Molecular Weight
152.15 g/mol
Also known as: Methyl 4-hydroxybenzoate, METHYLPARABEN, Methyl paraben, Methyl p-hydroxybenzoate, Nipagin
What does Methylparaben do for skin?
Methylparaben functions as a broad-spectrum antimicrobial preservative by inhibiting the growth of a wide range of microorganisms, including bacteria, yeasts, and molds. It achieves this by interfering with microbial cell membrane integrity, disrupting transport processes, and inhibiting specific enzyme systems crucial for microbial metabolism and replication, thereby preventing product spoilage and maintaining cosmetic stability and safety.
Typical concentration: 0.01-0.4% (most formulas use 0.1-0.3%, up to 0.8% total for paraben mixtures)
Is Methylparaben safe?
The Cosmetic Ingredient Review (CIR) Expert Panel has assessed methylparaben as safe for use in cosmetics at concentrations up to 0.4% individually and 0.8% for mixtures of parabens. It is generally well-tolerated, though rare instances of contact sensitization or irritation have been reported in individuals with compromised skin or specific allergies.
What does the research say about Methylparaben?
Safety Assessment of Parabens as Used in Cosmetics
Cosmetic Ingredient Review Expert Panel. International Journal of Toxicology, 2008
Parabens: a review of efficacy, safety and regulatory considerations
Soni MG, Taylor SL, Greenberg NA, Burdock GA. Food and Chemical Toxicology, 2001
Parabens and human epidermal keratinocytes: an in vitro study
Pizzino A, Tonnini C, Frazzette F, Grugni M, Zucchi R, D’Urso A. Dermatol Ther (Heidelb), 2021