beta-glucan
Humectant and skin-soothing ingredient with potential antioxidant properties.
What is beta-glucan?
CAS Number
9041-22-9
Formula
C18H32O16
Molecular Weight
504.4 g/mol
Also known as: beta-Glucan, RefChem:119378, GlyTouCan:G26190RC, DTXSID501019881, G26190RC
What does beta-glucan do for skin?
Beta-Glucan, a polysaccharide, effectively penetrates the epidermis to provide potent hydration by forming a hygroscopic film and binding water, similar to hyaluronic acid. It also functions as a biological response modifier, activating immune cells like macrophages and fibroblasts via specific receptors (e.g., Dectin-1) to promote wound healing, reduce inflammation, stimulate collagen synthesis, and enhance skin barrier function and elasticity.
Typical concentration: 0.05-2% (most cosmetic formulations use 0.1-1% for active benefits)
Is beta-glucan safe?
Beta-Glucan is generally recognized as safe and well-tolerated in cosmetic applications. The CIR Expert Panel has found beta-glucan to be safe for use in cosmetics, noting a low potential for irritation or sensitization.
What does the research say about beta-glucan?
Biological Activities of Beta-Glucan in Skin: Evidence and Insights.
Kim HS, et al. Ann Dermatol. 2021 Mar;33(2):162-172.
Topical applications of beta-glucans for skin and mucosal diseases.
Du Z, et al. Front Immunol. 2023 Feb 1;14:1107775.
Pyo SM, et al. J Cosmet Sci. 2012 Nov-Dec;63(6):387-95.