beta-glucan

Goodhumectant

Humectant and skin-soothing ingredient with potential antioxidant properties.

What is beta-glucan?

CAS Number

9041-22-9

Formula

C18H32O16

Molecular Weight

504.4 g/mol

Also known as: beta-Glucan, RefChem:119378, GlyTouCan:G26190RC, DTXSID501019881, G26190RC

What does beta-glucan do for skin?

Beta-Glucan, a polysaccharide, effectively penetrates the epidermis to provide potent hydration by forming a hygroscopic film and binding water, similar to hyaluronic acid. It also functions as a biological response modifier, activating immune cells like macrophages and fibroblasts via specific receptors (e.g., Dectin-1) to promote wound healing, reduce inflammation, stimulate collagen synthesis, and enhance skin barrier function and elasticity.

Typical concentration: 0.05-2% (most cosmetic formulations use 0.1-1% for active benefits)

Is beta-glucan safe?

Beta-Glucan is generally recognized as safe and well-tolerated in cosmetic applications. The CIR Expert Panel has found beta-glucan to be safe for use in cosmetics, noting a low potential for irritation or sensitization.

What does the research say about beta-glucan?

Regulatory Info

Status: Approved
Restrictions: beta-Glucan is a polysaccharide consisting of b(1-3) linked glucose chains carrying b(1-6) linked glucose sidechains

Frequently Asked Questions

What does beta-glucan do in skincare?+

Humectant and skin-soothing ingredient with potential antioxidant properties. Beta-Glucan, a polysaccharide, effectively penetrates the epidermis to provide potent hydration by forming a hygroscopic film and binding water, similar to hyaluronic acid. It also functions as a biological response modifier, activating immune cells like macrophages and fibroblasts via specific receptors (e.g., Dectin-1) to promote wound healing, reduce inflammation, stimulate collagen synthesis, and enhance skin barrier function and elasticity.

Is beta-glucan safe for sensitive skin?+

Beta-Glucan is generally recognized as safe and well-tolerated in cosmetic applications. The CIR Expert Panel has found beta-glucan to be safe for use in cosmetics, noting a low potential for irritation or sensitization.

What percentage of beta-glucan should I look for?+

Look for products with 0.05-2% (most cosmetic formulations use 0.1-1% for active benefits) for clinical efficacy.

Further Reading