Sodium Benzoate
소듐벤조에이트
Preservative that inhibits the growth of bacteria, mold, and yeast.
What is Sodium Benzoate?
CAS Number
532-32-1
Formula
C7H5NaO2
Molecular Weight
144.10 g/mol
Also known as: sodium benzoate, Sobenate, Antimol, Benzoic acid, sodium salt, sodium;benzoate
What does Sodium Benzoate do for skin?
Sodium Benzoate functions as a broad-spectrum antimicrobial preservative in cosmetic formulations. Its efficacy relies on its conversion to benzoic acid in acidic environments (pH < 4.5). Benzoic acid, being lipophilic, readily penetrates microbial cell membranes. Once inside the cell, it dissociates, acidifying the intracellular environment and inhibiting crucial microbial enzyme systems, such as those involved in oxidative phosphorylation and glucose uptake. This disruption of intracellular pH and metabolic processes effectively inhibits the growth of yeasts, molds, and some bacteria, thereby preventing product spoilage and potential microbial contamination on the skin.
Typical concentration: 0.1-1.0% (most formulas use 0.1-0.5%). The EU's maximum permitted concentration as benzoic acid is 0.5% in rinse-off and leave-on products, except for mouthwash where it is 1.7%.
Is Sodium Benzoate safe?
The CIR Expert Panel has concluded Sodium Benzoate is safe as a cosmetic ingredient in the present practices of use and concentration. It is generally recognized as safe (GRAS) by the FDA as a food additive. While generally well-tolerated, rare cases of contact urticaria or allergic reactions have been reported, primarily in individuals with pre-existing sensitivities.
What does the research say about Sodium Benzoate?
Final report on the safety assessment of benzyl alcohol, benzoic acid, and sodium benzoate.
Johnson W Jr, Bergfeld WF, Belsito D, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Int J Toxicol. 2001;20 Suppl 3:23-50.
Current antimicrobial preservative use in cosmetic and toiletry products.
Warne TR. J Cosmetic Sci. 2006 Nov-Dec;57(6):449-62.
Contact urticaria from sodium benzoate: a case report.
van der Beek MG, van Joost RA. Contact Dermatitis. 1999 Aug;41(2):106-7.