Octisalate

A UV-B filter that absorbs sunlight to protect the skin. Octisalate is an organic chemical UV filter that functions primarily by absorbing UVB radiation (280-320 nm). Its molecular structure contains chromophores, specifically an esterified salicylate group, which absorb high-energy UV photons. This absorbed energy is then dissipated through a process of molecular excitation and subsequent relaxation, often involving photoisomerization and vibrational relaxation, converting the harmful UV energy into lower-energy, non-damaging heat, thus protecting skin cells from UV-induced damage.

Octisalate (as Ethylhexyl Salicylate) is generally recognized as safe and effective (GRASE) by the FDA for use as a sunscreen active. The Cosmetic Ingredient Review (CIR) Expert Panel concluded that it is safe as used in cosmetic formulations. It is generally well-tolerated with a low potential for skin irritation or sensitization.

Look for products with 4-5% (most formulas use 4.5-5%). In the US, it is approved by the FDA as an OTC sunscreen active ingredient up to 5%. In the EU, it is permitted up to 5% in cosmetic sunscreens. for clinical efficacy.