Mannitol

OKhumectant

Humectant that draws moisture into the skin.

What is Mannitol?

CAS Number

69-65-8

Formula

C6H14O6

Molecular Weight

182.17 g/mol

Also known as: D-mannitol, mannitol, Mannite, Osmitrol, Manna sugar

What does Mannitol do for skin?

Mannitol functions primarily as a humectant in cosmetic formulations, drawing and retaining water from the environment into the stratum corneum, thereby enhancing skin hydration and maintaining barrier integrity. It also acts as an antioxidant, scavenging free radicals and reactive oxygen species, which helps to protect skin cells from oxidative stress and environmental damage. Its osmotic properties can also contribute to temporary plumping effects or serve as an excipient in formulations.

Typical concentration: 0.5-5% (commonly 1-3% for humectant/antioxidant effects)

Is Mannitol safe?

Mannitol is generally considered safe for topical use in cosmetics. It is a sugar alcohol widely used in food and pharmaceuticals and is recognized as safe (GRAS) by the FDA for oral consumption. The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Mannitol, but its extensive use history and low toxicity profile suggest minimal irritation or sensitization potential.

What does the research say about Mannitol?

Regulatory Info

Status: Approved
Restrictions: D-Mannitol
All Ingredients

Frequently Asked Questions

What does Mannitol do in skincare?+

Humectant that draws moisture into the skin. Mannitol functions primarily as a humectant in cosmetic formulations, drawing and retaining water from the environment into the stratum corneum, thereby enhancing skin hydration and maintaining barrier integrity. It also acts as an antioxidant, scavenging free radicals and reactive oxygen species, which helps to protect skin cells from oxidative stress and environmental damage. Its osmotic properties can also contribute to temporary plumping effects or serve as an excipient in formulations.

Is Mannitol safe for sensitive skin?+

Mannitol is generally considered safe for topical use in cosmetics. It is a sugar alcohol widely used in food and pharmaceuticals and is recognized as safe (GRAS) by the FDA for oral consumption. The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Mannitol, but its extensive use history and low toxicity profile suggest minimal irritation or sensitization potential.

What percentage of Mannitol should I look for?+

Look for products with 0.5-5% (commonly 1-3% for humectant/antioxidant effects) for clinical efficacy.