Lysine
An amino acid that plays a role in collagen production and skin repair.
What is Lysine?
CAS Number
56-87-1
Formula
C6H14N2O2
Molecular Weight
146.19 g/mol
Also known as: L-lysine, lysine, lysine acid, h-Lys-oh, (S)-Lysine
What does Lysine do for skin?
Lysine, as an essential amino acid, primarily functions as a humectant in cosmetic formulations, attracting and retaining water in the stratum corneum to enhance skin hydration and support barrier function. It is a fundamental building block for proteins like collagen and elastin, contributing to the skin's structural integrity. Additionally, lysine can be incorporated into peptides that may act as signaling molecules, potentially aiding in skin repair processes and contributing to overall skin health.
Typical concentration: 0.1-5% (most commonly found in complex amino acid blends or NMF-mimicking formulations; individual lysine concentration often ranges from 0.1-1%)
Is Lysine safe?
Lysine is an essential amino acid naturally present in the skin and generally recognized as safe for topical use. The CIR Expert Panel has concluded that amino acids, including Lysine, are safe as cosmetic ingredients. It exhibits a very low potential for skin irritation or sensitization.
What does the research say about Lysine?
Role of amino acids in natural moisturizing factor and skin hydration
Sato, J., et al. Journal of Dermatological Science, 1998
Egawa, M., et al. Archives of Dermatological Research, 2007
The role of amino acids in the epidermal barrier function
Coderch, L., et al. Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012