Linalool
리날룰
A fragrance ingredient that can be a potential skin irritant.
What is Linalool?
CAS Number
78-70-6
Formula
C10H18O
Molecular Weight
154.25 g/mol
Also known as: Linalool, Linalol, LINALYL ALCOHOL, beta-Linalool, allo-Ocimenol
What does Linalool do for skin?
Linalool's primary cosmetic function is as a fragrance component, providing a floral and woody scent profile through interaction with olfactory receptors. On skin, it exhibits mild antimicrobial activity, potentially by disrupting microbial cell membranes. It has also been reported to possess anti-inflammatory properties, possibly by modulating inflammatory pathways or interacting with transient receptor potential (TRP) channels, although these effects are generally secondary to its role as a scent agent in cosmetic formulations.
Typical concentration: Typically ranges from 0.001% to 1% in most cosmetic formulations, with concentrations potentially higher in dedicated fragrance products like perfumes. EU regulations require individual labeling of Linalool when its concentration exceeds 0.001% in leave-on products and 0.01% in rinse-off products.
Is Linalool safe?
The CIR Expert Panel considers Linalool safe as a cosmetic ingredient in the present practices of use and concentration. However, Linalool is a common contact allergen, particularly when oxidized by air, and is one of the 26 fragrance allergens mandated for individual labeling in the EU due to its sensitization potential in susceptible individuals.
What does the research say about Linalool?
Oxidation products of linalool, a common fragrance material, are potent contact allergens.
Karlberg AT, Bergström MA, Luthman K, Nilsson U, Nyman G, Börje A. Contact Dermatitis. 2007 Jul;57(1):32-8.
Choi EM, Hwang JK. Life Sci. 2011 May 9;88(19-20):809-15.
Safety Assessment of Fragrance Ingredients as Used in Cosmetics.
Expert Panel for Cosmetic Ingredient Safety. Int J Toxicol. 2018 Mar;37(1_suppl):5S-79S.