Licorice Root Extract
Known for its soothing, anti-inflammatory, and brightening properties.
What does Licorice Root Extract do for skin?
Licorice Root Extract (Glycyrrhiza glabra) acts on skin primarily through its active compounds, glabridin and licochalcone A. Glabridin inhibits tyrosinase activity without cytotoxicity, reducing melanin synthesis and providing a skin brightening effect. Licochalcone A exhibits potent anti-inflammatory properties by inhibiting the production of reactive oxygen species (ROS) and modulating inflammatory mediators, thereby soothing irritated skin and reducing redness. The extract also functions as an antioxidant, scavenging free radicals and protecting the skin from oxidative stress caused by environmental factors.
Typical concentration: 0.5-5% (many formulations use 1-3%)
Is Licorice Root Extract safe?
The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Glycyrrhiza Glabra (Licorice) Root Extract and related ingredients safe in current cosmetic uses and concentrations. It is generally well-tolerated with low potential for irritation or sensitization in topical applications.
What does the research say about Licorice Root Extract?
The inhibitory effect of glabridin from licorice extracts on melanogenesis and inflammation
Yokota T, Nishio H, Kubota Y, Mizoguchi M. Pigment Cell Res. 1998 Aug;11(4):220-9.
Kim J, Kim EJ, Park J, Kim YJ, Park H, Son HY. J Photochem Photobiol B. 2013 Aug 5;125:128-35.
Licochalcone A: a new skin-lightening agent from licorice extract for hyperpigmentation treatment
Kolbe L, Kligman AM, Kaden D, Bielfeldt S, Böhling A, Glombik M, Lübbert R, Wenck H, Stäb F. J Cosmet Sci. 2006 Jan-Feb;57(1):63-7.