Lecithin
An emulsifier and skin-conditioning agent that helps stabilize formulations and improve texture.
What is Lecithin?
CAS Number
97281-47-5
Formula
C42H80NO8P
Molecular Weight
758.1 g/mol
Also known as: LECITHIN, Lecithin (NF), Lecithin [NF], Granulestin, Ovovitellin
What does Lecithin do for skin?
Lecithin, primarily composed of phospholipids, acts as a versatile emulsifier in cosmetic formulations, reducing interfacial tension between immiscible phases (oil and water) to create and stabilize emulsions. On the skin, its amphiphilic nature allows it to function as a skin-conditioning agent, contributing to barrier repair and hydration by integrating into the lipid lamellae of the stratum corneum. Moreover, lecithin is a crucial component in advanced delivery systems like liposomes and nanosomes, encapsulating active ingredients and facilitating their enhanced penetration into the epidermis, thereby improving their bioavailability and efficacy.
Typical concentration: 0.5-10% (most formulas use 1-5% for emulsifying or skin conditioning purposes; higher concentrations may be used in specialized delivery systems).
Is Lecithin safe?
The CIR (Cosmetic Ingredient Review) Expert Panel has assessed Lecithin and related phospholipids as safe for use in cosmetics. It is generally well-tolerated with low potential for irritation or sensitization.
What does the research say about Lecithin?
Proksch E, Nissen HP, Schwab P, et al. J Dermatolog Treat. 2008;19(1):2-7.
El-Say KM, Abd-Allah FI, Helmy MW, Amer RI. Int J Pharm. 2017 Aug 15;528(1-2):50-60.
Lecithin and the Skin: A Review of Interactions and Clinical Properties.
Wigger-Alberti W, Schmieder A. Skin Pharmacol Physiol. 2005 Nov-Dec;18(6):264-70.