Hypromellose
Thickener and film-former.
What does Hypromellose do for skin?
Hypromellose (Hydroxypropyl Methylcellulose, HPMC) functions primarily as a film-former, viscosity-increasing agent, binder, and emulsion stabilizer in cosmetic formulations. Upon application, it forms a clear, flexible film on the skin or hair surface, contributing to a smoother feel, improved spreadability, and potential for transepidermal water loss reduction through an occlusive effect. In aqueous solutions, HPMC creates a polymeric network that increases viscosity, enabling the stabilization of emulsions and the suspension of insoluble particles, thereby enhancing product texture and stability.
Typical concentration: 0.1-5% (most formulas use 0.5-2%)
Is Hypromellose safe?
The Cosmetic Ingredient Review (CIR) Expert Panel assessed Hypromellose (as part of cellulose and its derivatives) and concluded it is safe as a cosmetic ingredient. It is generally considered non-irritating and non-sensitizing for topical use.
What does the research say about Hypromellose?
Safety Assessment of Cellulose and Its Derivatives as Used in Cosmetics
CIR Expert Panel, International Journal of Toxicology, 2011
Kou X, Liu J, Ma H, Jin Z, J Pharm Sci, 2005
Tuncay M, Aytemir MD, Karadag-Caman OK, Ozdemir F, Demir B, Pharmazie, 2014