Glycine

Goodhumectant

An amino acid that acts as a humectant and skin-conditioning agent.

What is Glycine?

CAS Number

56-40-6

Formula

C2H5NO2

Molecular Weight

75.07 g/mol

Also known as: glycine, aminoacetic acid, Aminoethanoic acid, Glycocoll, Glycolixir

What does Glycine do for skin?

Glycine, a small non-essential amino acid, serves as a key component of the Natural Moisturizing Factor (NMF) in the stratum corneum. It functions as a humectant, effectively attracting and binding water within the skin, thereby enhancing hydration and supporting the skin's barrier function. Additionally, it acts as a fundamental building block for proteins like collagen and elastin, contributing to skin structure and elasticity, and exhibits some antioxidant properties.

Typical concentration: 0.1-5% (commonly used at 0.5-2% in NMF-mimicking complexes or skin conditioning blends).

Is Glycine safe?

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed glycine and found it safe for use in cosmetics. As a naturally occurring amino acid in the body, it has a very low potential for irritation or sensitization.

What does the research say about Glycine?

Regulatory Info

Status: Approved
Restrictions: Glycine
All Ingredients

Frequently Asked Questions

What does Glycine do in skincare?+

An amino acid that acts as a humectant and skin-conditioning agent. Glycine, a small non-essential amino acid, serves as a key component of the Natural Moisturizing Factor (NMF) in the stratum corneum. It functions as a humectant, effectively attracting and binding water within the skin, thereby enhancing hydration and supporting the skin's barrier function. Additionally, it acts as a fundamental building block for proteins like collagen and elastin, contributing to skin structure and elasticity, and exhibits some antioxidant properties.

Is Glycine safe for sensitive skin?+

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed glycine and found it safe for use in cosmetics. As a naturally occurring amino acid in the body, it has a very low potential for irritation or sensitization.

What percentage of Glycine should I look for?+

Look for products with 0.1-5% (commonly used at 0.5-2% in NMF-mimicking complexes or skin conditioning blends). for clinical efficacy.