Elastin

Protein that provides elasticity to the skin, though its topical effectiveness is debated. Topical elastin, due to its high molecular weight, does not penetrate the stratum corneum to integrate into endogenous dermal elastin fibers or stimulate new elastin synthesis. Instead, it functions primarily as a film-forming agent on the skin surface. This hygroscopic, non-occlusive film attracts and retains water, thereby enhancing skin hydration, improving suppleness, and providing a temporary smoothing and mild tightening effect on the skin's appearance.

The Cosmetic Ingredient Review (CIR) Expert Panel assessed elastin and hydrolyzed elastin as safe for use in cosmetics under current conditions. It is generally considered non-irritating and non-sensitizing due to its large molecular size limiting skin penetration.

Look for products with 0.1-2% (of active protein, often supplied in solutions like 5-10% of which 2-20% is incorporated into the final product). for clinical efficacy.