Edta
Chelating agent that binds metal ions, improving product stability and efficacy.
What is Edta?
CAS Number
139-33-3
Formula
C10H14N2Na2O8
Molecular Weight
336.21 g/mol
Also known as: EDTA disodium salt, Disodium EDTA, Disodium ethylenediaminetetraacetate, EDTA 2Na, MFCD00070672
What does Edta do for skin?
Disodium EDTA functions as a chelating agent (sequestering agent) in cosmetic formulations. It binds to polyvalent metal ions, such as calcium, magnesium, and iron, preventing them from interacting with other ingredients. This chelation activity stabilizes the product by inhibiting metal-catalyzed oxidation reactions that can lead to rancidity, discoloration, and degradation of sensitive ingredients, thereby extending shelf-life and maintaining product integrity and efficacy. It also improves the efficacy of preservatives and surfactant performance by sequestering hardness ions in water.
Typical concentration: 0.05-0.5% (most formulas use 0.1-0.2%)
Is Edta safe?
The CIR Expert Panel has assessed disodium EDTA and its salts as safe for use in cosmetics. It is generally considered non-irritating and non-sensitizing, though it can enhance the dermal penetration of other ingredients, which is typically considered during formulation.
What does the research say about Edta?
Safety assessment of EDTA and its salts as used in cosmetics
Elder RL, Belsito DV, De S. Johnson W, et al. Int J Toxicol. 2011 Nov;30(6 Suppl):83S-92S.
Final report on the safety assessment of EDTA and its salts
J Am Coll Toxicol. 1981;1(2):1-40.