Biotin
Vitamin B7, known for its role in cell metabolism and hair/nail health, can benefit skin.
What is Biotin?
CAS Number
58-85-5
Formula
C10H16N2O3S
Molecular Weight
244.31 g/mol
Also known as: biotin, d-biotin, vitamin H, Vitamin B7, Bioepiderm
What does Biotin do for skin?
Biotin (Vitamin B7) functions as a coenzyme for carboxylase enzymes that are vital for key metabolic pathways, including fatty acid synthesis, gluconeogenesis, and amino acid catabolism. In the context of skin, hair, and nails, it supports the production of keratin, a primary structural protein, and the synthesis of lipids crucial for maintaining a healthy skin barrier. By facilitating these essential cellular processes, biotin helps ensure the proper development and maintenance of skin cells, hair follicles, and nail matrices, contributing to overall skin integrity and strength.
Typical concentration: 0.0001-0.1% (most cosmetic formulations use 0.001-0.01%)
Is Biotin safe?
Biotin is considered safe for topical cosmetic use and is well-tolerated at typical concentrations. No significant irritation or sensitization potential has been reported. While the CIR Expert Panel has not conducted a specific safety assessment on biotin as a cosmetic ingredient, it is an essential vitamin with a long history of safe use.
What does the research say about Biotin?
Oral Biotin Supplementation in the Treatment of Brittle Nails and Hair: A Systematic Review
Patel DP, Swick BL, Patel DP, J Drugs Dermatol, 2017
The role of biotin in dermatology
Almohanna HM, Tsatalis JP, Ahmed AA, Tosti A, J Am Acad Dermatol, 2020
Biotin and biotinidase deficiency
Zempleni J, Hassan YI, Wijeratne SS, Expert Rev Endocrinol Metab, 2009